A physiologically based pharmacokinetic model for developmental exposure to BDE-47 in rats

Polybrominated diphenyl ethers (PBDEs) are used commercially as additive flame retardants and have been shown to transfer into environmental compartments, where they have the potential to bioaccumulate in wildlife and humans. Of the 209 possible PBDEs, 2,2′,4,4′-tetrabromodiphenyl ether (BDE-47) is...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Toxicology and applied pharmacology 2010-02, Vol.242 (3), p.290-298
Hauptverfasser:	Emond, Claude, Raymer, James H., Studabaker, William B., Garner, C. Edwin, Birnbaum, Linda S.
Format:	Artikel
Sprache:	eng
Schlagworte:	60 APPLIED LIFE SCIENCES ADIPOSE TISSUE ANIMAL TISSUES ANIMALS AROMATICS BDE-47 Biological and medical sciences BODY BRAIN BROMINATED AROMATIC HYDROCARBONS CENTRAL NERVOUS SYSTEM CONNECTIVE TISSUE Developmental exposure DIGESTIVE SYSTEM Environmental Pollutants - pharmacokinetics ETHERS Female FETAL MEMBRANES Fetus - metabolism FETUSES GLANDS HALOGENATED AROMATIC HYDROCARBONS Halogenated Diphenyl Ethers Humans KIDNEYS LIVER Male MALES MAMMALS MAN Maternal Exposure Maternal-Fetal Exchange Medical sciences MEMBRANES MEN Models, Biological NERVOUS SYSTEM ORGANIC BROMINE COMPOUNDS ORGANIC COMPOUNDS ORGANIC HALOGEN COMPOUNDS ORGANIC OXYGEN COMPOUNDS ORGANS PBPK Pharmacokinetics PHENYL ETHER PLACENTA Polybrominated Biphenyls - pharmacokinetics Polybrominated diphenyl ethers Pregnancy PRIMATES Rat RATS Rats, Sprague-Dawley RODENTS SIMULATION Species Specificity Tissue Distribution TOXICITY Toxicology VERTEBRATES
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!