Secondary Neutron Doses for Several Beam Configurations for Proton Therapy

Purpose To compare possible neutron doses produced in scanning and scattering modes, with the latter assessed using a newly built passive-scattering proton beam line. Methods and Materials A 40 × 30.5 × 30-cm water phantom was irradiated with 230-MeV proton beams using a gantry angle of 270°, a 10-c...

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Veröffentlicht in:International journal of radiation oncology, biology, physics biology, physics, 2009-05, Vol.74 (1), p.260-265
Hauptverfasser: Shin, Dongho, Ph.D, Yoon, Myonggeun, Ph.D, Kwak, Jungwon, Ph.D, Shin, Jungwook, Ph.D, Lee, Se Byeong, Ph.D, Park, Sung Yong, Ph.D, Park, Soah, Ph.D, Kim, Dae Yong, M.D, Cho, Kwan Ho, M.D
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container_issue 1
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container_title International journal of radiation oncology, biology, physics
container_volume 74
creator Shin, Dongho, Ph.D
Yoon, Myonggeun, Ph.D
Kwak, Jungwon, Ph.D
Shin, Jungwook, Ph.D
Lee, Se Byeong, Ph.D
Park, Sung Yong, Ph.D
Park, Soah, Ph.D
Kim, Dae Yong, M.D
Cho, Kwan Ho, M.D
description Purpose To compare possible neutron doses produced in scanning and scattering modes, with the latter assessed using a newly built passive-scattering proton beam line. Methods and Materials A 40 × 30.5 × 30-cm water phantom was irradiated with 230-MeV proton beams using a gantry angle of 270°, a 10-cm-diameter snout, and a brass aperture with a diameter of 7 cm and a thickness of 6.5 cm. The secondary neutron doses during irradiation were measured at various points using CR-39 detectors, and these measurements were cross-checked using a neutron survey meter with a 22-cm range and a 5-cm spread-out Bragg peak. Results The maximum doses due to secondary neutrons produced by a scattering beam-delivery system were on the order of 0.152 mSv/Gy and 1.17 mSv/Gy at 50 cm from the beam isocenter in the longitudinal (0°) and perpendicular (90°) directions, respectively. The neutron dose equivalent to the proton absorbed dose, measured from 10 cm to 100 cm from the isocenter, ranged from 0.071 mSv/Gy to 1.96 mSv/Gy in the direction of the beam line ( i.e., φ = 0°). The largest neutron dose, of 3.88 mSv/Gy, was observed at 135° and 25 cm from the isocenter. Conclusions Although the secondary neutron doses in proton therapy were higher when a scattering mode rather than a scanning mode was used, they did not exceed the scattered photon dose in typical photon treatments.
doi_str_mv 10.1016/j.ijrobp.2008.10.090
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Methods and Materials A 40 × 30.5 × 30-cm water phantom was irradiated with 230-MeV proton beams using a gantry angle of 270°, a 10-cm-diameter snout, and a brass aperture with a diameter of 7 cm and a thickness of 6.5 cm. The secondary neutron doses during irradiation were measured at various points using CR-39 detectors, and these measurements were cross-checked using a neutron survey meter with a 22-cm range and a 5-cm spread-out Bragg peak. Results The maximum doses due to secondary neutrons produced by a scattering beam-delivery system were on the order of 0.152 mSv/Gy and 1.17 mSv/Gy at 50 cm from the beam isocenter in the longitudinal (0°) and perpendicular (90°) directions, respectively. The neutron dose equivalent to the proton absorbed dose, measured from 10 cm to 100 cm from the isocenter, ranged from 0.071 mSv/Gy to 1.96 mSv/Gy in the direction of the beam line ( i.e., φ = 0°). The largest neutron dose, of 3.88 mSv/Gy, was observed at 135° and 25 cm from the isocenter. Conclusions Although the secondary neutron doses in proton therapy were higher when a scattering mode rather than a scanning mode was used, they did not exceed the scattered photon dose in typical photon treatments.</description><identifier>ISSN: 0360-3016</identifier><identifier>EISSN: 1879-355X</identifier><identifier>DOI: 10.1016/j.ijrobp.2008.10.090</identifier><identifier>PMID: 19362245</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>BRAGG CURVE ; Calibration ; CR-39 ; Elementary Particle Interactions ; Hematology, Oncology and Palliative Medicine ; Humans ; MEV RANGE 100-1000 ; Neutron dose ; NEUTRONS ; Neutrons - adverse effects ; PHANTOMS ; Phantoms, Imaging ; PHOTONS ; Proton ; PROTON BEAMS ; PROTONS ; Protons - therapeutic use ; RADIATION DOSES ; Radiology ; RADIOLOGY AND NUCLEAR MEDICINE ; Radiometry - instrumentation ; RADIOTHERAPY ; Radiotherapy Dosage ; Relative Biological Effectiveness ; SCATTERING ; Scattering, Radiation ; Secondary neutron</subject><ispartof>International journal of radiation oncology, biology, physics, 2009-05, Vol.74 (1), p.260-265</ispartof><rights>Elsevier Inc.</rights><rights>2009 Elsevier Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c509t-7c3eb1a9bfd1a4544aea29dc486483b4bfed4937fbfa749bb27982d99415e99c3</citedby><cites>FETCH-LOGICAL-c509t-7c3eb1a9bfd1a4544aea29dc486483b4bfed4937fbfa749bb27982d99415e99c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0360301609000959$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>230,314,776,780,881,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19362245$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://www.osti.gov/biblio/21276797$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>Shin, Dongho, Ph.D</creatorcontrib><creatorcontrib>Yoon, Myonggeun, Ph.D</creatorcontrib><creatorcontrib>Kwak, Jungwon, Ph.D</creatorcontrib><creatorcontrib>Shin, Jungwook, Ph.D</creatorcontrib><creatorcontrib>Lee, Se Byeong, Ph.D</creatorcontrib><creatorcontrib>Park, Sung Yong, Ph.D</creatorcontrib><creatorcontrib>Park, Soah, Ph.D</creatorcontrib><creatorcontrib>Kim, Dae Yong, M.D</creatorcontrib><creatorcontrib>Cho, Kwan Ho, M.D</creatorcontrib><title>Secondary Neutron Doses for Several Beam Configurations for Proton Therapy</title><title>International journal of radiation oncology, biology, physics</title><addtitle>Int J Radiat Oncol Biol Phys</addtitle><description>Purpose To compare possible neutron doses produced in scanning and scattering modes, with the latter assessed using a newly built passive-scattering proton beam line. Methods and Materials A 40 × 30.5 × 30-cm water phantom was irradiated with 230-MeV proton beams using a gantry angle of 270°, a 10-cm-diameter snout, and a brass aperture with a diameter of 7 cm and a thickness of 6.5 cm. The secondary neutron doses during irradiation were measured at various points using CR-39 detectors, and these measurements were cross-checked using a neutron survey meter with a 22-cm range and a 5-cm spread-out Bragg peak. Results The maximum doses due to secondary neutrons produced by a scattering beam-delivery system were on the order of 0.152 mSv/Gy and 1.17 mSv/Gy at 50 cm from the beam isocenter in the longitudinal (0°) and perpendicular (90°) directions, respectively. The neutron dose equivalent to the proton absorbed dose, measured from 10 cm to 100 cm from the isocenter, ranged from 0.071 mSv/Gy to 1.96 mSv/Gy in the direction of the beam line ( i.e., φ = 0°). The largest neutron dose, of 3.88 mSv/Gy, was observed at 135° and 25 cm from the isocenter. Conclusions Although the secondary neutron doses in proton therapy were higher when a scattering mode rather than a scanning mode was used, they did not exceed the scattered photon dose in typical photon treatments.</description><subject>BRAGG CURVE</subject><subject>Calibration</subject><subject>CR-39</subject><subject>Elementary Particle Interactions</subject><subject>Hematology, Oncology and Palliative Medicine</subject><subject>Humans</subject><subject>MEV RANGE 100-1000</subject><subject>Neutron dose</subject><subject>NEUTRONS</subject><subject>Neutrons - adverse effects</subject><subject>PHANTOMS</subject><subject>Phantoms, Imaging</subject><subject>PHOTONS</subject><subject>Proton</subject><subject>PROTON BEAMS</subject><subject>PROTONS</subject><subject>Protons - therapeutic use</subject><subject>RADIATION DOSES</subject><subject>Radiology</subject><subject>RADIOLOGY AND NUCLEAR MEDICINE</subject><subject>Radiometry - instrumentation</subject><subject>RADIOTHERAPY</subject><subject>Radiotherapy Dosage</subject><subject>Relative Biological Effectiveness</subject><subject>SCATTERING</subject><subject>Scattering, Radiation</subject><subject>Secondary neutron</subject><issn>0360-3016</issn><issn>1879-355X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkV1r2zAUhsVYWdJ0_2AMw66d6suWdVNY064fhLaQDHYnJPl4kZtYQXIK-feTcWDQm14Jjp73nPO-B6FvBM8JJuVlO3dt8GY_pxhXqTTHEn9CU1IJmbOi-PMZTTErcc4SPEHnMbYYY0IE_4ImRLKSUl5M0eMKrO9qHY7ZExz64LvsxkeIWeNDtoI3CHqbXYPeZQvfNe7vIeje-W78fwm-T4L1JlH74wU6a_Q2wtfTO0O_f92uF_f58vnuYfFzmdsCyz4XloEhWpqmJpoXnGvQVNaWVyWvmOGmgZpLJhrTaMGlMVTIitZSclKAlJbN0I-xr4-9U9G6HuwmmejA9ooSKkohRaL4SNngYwzQqH1wu-RTEayGAFWrxgDVEOBQTQEm2fdRtj-YHdT_RafEEnA1ApAsvjkIwwbQWahdGBaovftowvsGdus6Z_X2FY4QW38IXYpPERWpwmo1HHG4YdJiLAvJ_gHm9ZiX</recordid><startdate>20090501</startdate><enddate>20090501</enddate><creator>Shin, Dongho, Ph.D</creator><creator>Yoon, Myonggeun, Ph.D</creator><creator>Kwak, Jungwon, Ph.D</creator><creator>Shin, Jungwook, Ph.D</creator><creator>Lee, Se Byeong, Ph.D</creator><creator>Park, Sung Yong, Ph.D</creator><creator>Park, Soah, Ph.D</creator><creator>Kim, Dae Yong, M.D</creator><creator>Cho, Kwan Ho, M.D</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>OTOTI</scope></search><sort><creationdate>20090501</creationdate><title>Secondary Neutron Doses for Several Beam Configurations for Proton Therapy</title><author>Shin, Dongho, Ph.D ; Yoon, Myonggeun, Ph.D ; Kwak, Jungwon, Ph.D ; Shin, Jungwook, Ph.D ; Lee, Se Byeong, Ph.D ; Park, Sung Yong, Ph.D ; Park, Soah, Ph.D ; Kim, Dae Yong, M.D ; Cho, Kwan Ho, M.D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c509t-7c3eb1a9bfd1a4544aea29dc486483b4bfed4937fbfa749bb27982d99415e99c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>BRAGG CURVE</topic><topic>Calibration</topic><topic>CR-39</topic><topic>Elementary Particle Interactions</topic><topic>Hematology, Oncology and Palliative Medicine</topic><topic>Humans</topic><topic>MEV RANGE 100-1000</topic><topic>Neutron dose</topic><topic>NEUTRONS</topic><topic>Neutrons - adverse effects</topic><topic>PHANTOMS</topic><topic>Phantoms, Imaging</topic><topic>PHOTONS</topic><topic>Proton</topic><topic>PROTON BEAMS</topic><topic>PROTONS</topic><topic>Protons - therapeutic use</topic><topic>RADIATION DOSES</topic><topic>Radiology</topic><topic>RADIOLOGY AND NUCLEAR MEDICINE</topic><topic>Radiometry - instrumentation</topic><topic>RADIOTHERAPY</topic><topic>Radiotherapy Dosage</topic><topic>Relative Biological Effectiveness</topic><topic>SCATTERING</topic><topic>Scattering, Radiation</topic><topic>Secondary neutron</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Shin, Dongho, Ph.D</creatorcontrib><creatorcontrib>Yoon, Myonggeun, Ph.D</creatorcontrib><creatorcontrib>Kwak, Jungwon, Ph.D</creatorcontrib><creatorcontrib>Shin, Jungwook, Ph.D</creatorcontrib><creatorcontrib>Lee, Se Byeong, Ph.D</creatorcontrib><creatorcontrib>Park, Sung Yong, Ph.D</creatorcontrib><creatorcontrib>Park, Soah, Ph.D</creatorcontrib><creatorcontrib>Kim, Dae Yong, M.D</creatorcontrib><creatorcontrib>Cho, Kwan Ho, M.D</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>OSTI.GOV</collection><jtitle>International journal of radiation oncology, biology, physics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shin, Dongho, Ph.D</au><au>Yoon, Myonggeun, Ph.D</au><au>Kwak, Jungwon, Ph.D</au><au>Shin, Jungwook, Ph.D</au><au>Lee, Se Byeong, Ph.D</au><au>Park, Sung Yong, Ph.D</au><au>Park, Soah, Ph.D</au><au>Kim, Dae Yong, M.D</au><au>Cho, Kwan Ho, M.D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Secondary Neutron Doses for Several Beam Configurations for Proton Therapy</atitle><jtitle>International journal of radiation oncology, biology, physics</jtitle><addtitle>Int J Radiat Oncol Biol Phys</addtitle><date>2009-05-01</date><risdate>2009</risdate><volume>74</volume><issue>1</issue><spage>260</spage><epage>265</epage><pages>260-265</pages><issn>0360-3016</issn><eissn>1879-355X</eissn><abstract>Purpose To compare possible neutron doses produced in scanning and scattering modes, with the latter assessed using a newly built passive-scattering proton beam line. Methods and Materials A 40 × 30.5 × 30-cm water phantom was irradiated with 230-MeV proton beams using a gantry angle of 270°, a 10-cm-diameter snout, and a brass aperture with a diameter of 7 cm and a thickness of 6.5 cm. The secondary neutron doses during irradiation were measured at various points using CR-39 detectors, and these measurements were cross-checked using a neutron survey meter with a 22-cm range and a 5-cm spread-out Bragg peak. Results The maximum doses due to secondary neutrons produced by a scattering beam-delivery system were on the order of 0.152 mSv/Gy and 1.17 mSv/Gy at 50 cm from the beam isocenter in the longitudinal (0°) and perpendicular (90°) directions, respectively. The neutron dose equivalent to the proton absorbed dose, measured from 10 cm to 100 cm from the isocenter, ranged from 0.071 mSv/Gy to 1.96 mSv/Gy in the direction of the beam line ( i.e., φ = 0°). The largest neutron dose, of 3.88 mSv/Gy, was observed at 135° and 25 cm from the isocenter. Conclusions Although the secondary neutron doses in proton therapy were higher when a scattering mode rather than a scanning mode was used, they did not exceed the scattered photon dose in typical photon treatments.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>19362245</pmid><doi>10.1016/j.ijrobp.2008.10.090</doi><tpages>6</tpages></addata></record>
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identifier ISSN: 0360-3016
ispartof International journal of radiation oncology, biology, physics, 2009-05, Vol.74 (1), p.260-265
issn 0360-3016
1879-355X
language eng
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source MEDLINE; Elsevier ScienceDirect Journals
subjects BRAGG CURVE
Calibration
CR-39
Elementary Particle Interactions
Hematology, Oncology and Palliative Medicine
Humans
MEV RANGE 100-1000
Neutron dose
NEUTRONS
Neutrons - adverse effects
PHANTOMS
Phantoms, Imaging
PHOTONS
Proton
PROTON BEAMS
PROTONS
Protons - therapeutic use
RADIATION DOSES
Radiology
RADIOLOGY AND NUCLEAR MEDICINE
Radiometry - instrumentation
RADIOTHERAPY
Radiotherapy Dosage
Relative Biological Effectiveness
SCATTERING
Scattering, Radiation
Secondary neutron
title Secondary Neutron Doses for Several Beam Configurations for Proton Therapy
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