Production of PET radionuclides using a 10.5 MeV {sup 3}He RFQ accelerator

An RFQ linac has been built that accelerates {sup 3}He to 10.5 MeV for production of C, N, O, F isotopes for PET. The accelerator produces 70 {mu}s pulses, at 360 Hz, a 2.5% duty cycle, with a peak current of {approx}6 mAe. The RFQ delivers {approx}100 {mu}Ae. A recirculating water target has been e...

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Veröffentlicht in:AIP conference proceedings 1999-06, Vol.475 (1)
Hauptverfasser: Link, Jeanne M., Krohn, Kenneth A., Bida, Jerry T., DeHaas, Richard, Larson, Delbert J., Johanning, Jeff, Young, Phillip E., Pasquinelli, Ralph J.
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Sprache:eng
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Zusammenfassung:An RFQ linac has been built that accelerates {sup 3}He to 10.5 MeV for production of C, N, O, F isotopes for PET. The accelerator produces 70 {mu}s pulses, at 360 Hz, a 2.5% duty cycle, with a peak current of {approx}6 mAe. The RFQ delivers {approx}100 {mu}Ae. A recirculating water target has been evaluated for production of {sup 18}F and low specific activity {sup 15}O. Recoil chemistry within the target has been evaluated to improve {sup 15}O specific activity. Gas targets have also been tested for production of {sup 15}O. {sup 13}N is made from carbon. Several target materials have been evaluated for producing {sup 11}C, including C, B and Be. The challenges of targetry for this high current, low energy machine led us to evaluate large, high aspect ratio windows and grid supports. The {sup 3}He RFQ is a useful research machine for testing targets for pulsed, high power density, low LET beams.
ISSN:0094-243X
1551-7616
DOI:10.1063/1.59091