Use of Palliative Radiotherapy Among Patients With Metastatic Non–Small-Cell Lung Cancer

Purpose Radiotherapy (RT) is known to effectively palliate many symptoms of patients with metastatic non–small-cell lung cancer (NSCLC). Anecdotally, RT is believed to be commonly used in this setting, but limited population-based data are available. The objective of this study was to examine the ut...

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Veröffentlicht in:International journal of radiation oncology, biology, physics biology, physics, 2007-11, Vol.69 (4), p.1001-1007
Hauptverfasser: Hayman, James A., M.D., M.B.A, Abrahamse, Paul H., M.A, Lakhani, Indu, M.S, Earle, Craig C., M.D., M.Sc., F.R.C.P.C, Katz, Steven J., M.D., M.P.H
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Sprache:eng
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Zusammenfassung:Purpose Radiotherapy (RT) is known to effectively palliate many symptoms of patients with metastatic non–small-cell lung cancer (NSCLC). Anecdotally, RT is believed to be commonly used in this setting, but limited population-based data are available. The objective of this study was to examine the utilization patterns of palliative RT among elderly patients with Stage IV NSCLC and, in particular, to identify factors associated with its use. Methods and Materials A retrospective population-based cohort study was performed using linked Surveillance, Epidemiology and End Results (SEER)-Medicare data to identify 11,084 Medicare beneficiaries aged ≥65 years who presented with Stage IV NSCLC in the 11 SEER regions between 1991 and 1996. The primary outcome was receipt of RT. Logistic regression analysis was used to identify factors associated with receipt of RT. Results A total of 58% of these patients received RT, with its use decreasing over time ( p = 0.01). Increasing age was negatively associated with receipt of treatment ( p
ISSN:0360-3016
1879-355X
DOI:10.1016/j.ijrobp.2007.04.059