Structure and properties of DOTA-chelated radiopharmaceuticals within the 225 Ac decay pathway

Structure and properties of DOTA-chelated radiopharmaceuticals within the 225 Ac decay pathway

The stability of DOTA-chelated complexes coordinated with H2O has a strong correlation between the opening angle of DOTA and the atomic mass of the radioactive isotope.

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Veröffentlicht in:MedChemComm 2018-01, Vol.9 (7)
Hauptverfasser: Khabibullin, Artem R., Karolak, Aleksandra, Budzevich, Mikalai M., McLaughlin, Mark L., Morse, David L., Woods, Lilia M.
Format: Artikel
Sprache:eng
Schlagworte:
Biochemistry & Molecular Biology
Pharmacology & Pharmacy
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Zusammenfassung:The stability of DOTA-chelated complexes coordinated with H2O has a strong correlation between the opening angle of DOTA and the atomic mass of the radioactive isotope.
ISSN:2040-2503
2040-2511
DOI:10.1039/c8md00170g