Nondisruptive Dissolution of Hyperpolarized 129Xe into Viscous Aqueous and Organic Liquid Crystalline Environments

Studies of hyperpolarized xenon‐129 (hp‐129Xe) in media such as liquid crystals and cell suspensions are in demand for applications ranging from biomedical imaging to materials engineering but have been hindered by the inability to bubble Xe through the desired media as a result of viscosity or pert...

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Veröffentlicht in:	Angewandte Chemie (International ed.) 2016-04, Vol.55 (15), p.4666-4670
Hauptverfasser:	Truxal, Ashley E., Slack, Clancy C., Gomes, Muller D., Vassiliou, Christophoros C., Wemmer, David E., Pines, Alexander
Format:	Artikel
Sprache:	eng
Schlagworte:	Alignment Biomedical engineering Biomedical materials Bubbles Bubbling Cell suspensions Compatibility Crystal structure Crystals Demand Disruption Dissolution Hardware hyperpolarization INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY liquid crystal Liquid crystals Magnetic resonance spectroscopy Materials engineering Media NMR NMR spectroscopy Phase transitions Robustness Shear Viscosity viscous solution Xenon
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Beschreibung
Zusammenfassung:	Studies of hyperpolarized xenon‐129 (hp‐129Xe) in media such as liquid crystals and cell suspensions are in demand for applications ranging from biomedical imaging to materials engineering but have been hindered by the inability to bubble Xe through the desired media as a result of viscosity or perturbations caused by bubbles. Herein a device is reported that can be reliably used to dissolve hp‐129Xe into viscous aqueous and organic samples without bubbling. This method is robust, requires small sample volumes (
ISSN:	1433-7851 1521-3773
DOI:	10.1002/anie.201511539