Single-Amino Acid Modifications Reveal Additional Controls on the Proton Pathway of [FeFe]-Hydrogenase

The proton pathway of [FeFe]-hydrogenase is essential for enzymatic H2 production and oxidation and is composed of four residues and a water molecule. A computational analysis of this pathway in the [FeFe]-hydrogenase from Clostridium pasteurianum revealed that the solvent-exposed residue of the pat...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biochemistry (Easton) 2016-06, Vol.55 (22), p.3165-3173
Hauptverfasser:	Cornish, Adam J, Ginovska, Bojana, Thelen, Adam, da Silva, Julio C. S, Soares, Thereza A, Raugei, Simone, Dupuis, Michel, Shaw, Wendy J, Hegg, Eric L
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acids - chemistry Amino Acids - genetics Bacterial Proteins - chemistry Bacterial Proteins - genetics Bacterial Proteins - metabolism catalysis Clostridium - enzymology hydrogenase Hydrogenase - chemistry Hydrogenase - genetics Hydrogenase - metabolism Ion Transport Iron - metabolism Iron-Sulfur Proteins - chemistry Iron-Sulfur Proteins - genetics Iron-Sulfur Proteins - metabolism Molecular Dynamics Simulation Mutagenesis, Site-Directed Mutant Proteins - chemistry Mutant Proteins - genetics Mutant Proteins - metabolism Mutation - genetics outer coordination sphere proton pathway Protons
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!