Dihydro-resveratrol—A potent dietary polyphenol

Dihydro-resveratrol, a prominent polyphenol component of red wine, has a profound proliferative effect on hormone-sensitive tumor cell lines at picomolar concentrations. Dihydro-resveratrol ( dihydro- R), a prominent polyphenol component of red wine, has a profound proliferative effect on hormone-sensitive tumor cell lines such as breast cancer cell line MCF7. We found a significant increase in MCF7 tumor cells growth rates in the presence of picomolar concentrations of this compound. The proliferative effect of dihydro- R was not observed in cell lines that do not express hormone receptors (MDA-MB-231, BT-474, and К-562).