Clinical, Pathological, and Molecular Characteristics in Colorectal Cancer

Despite major medical advances in recent decades, colorectal cancer remains a major public health problem with significant unmet medical needs. This reprint presents new scientific and clinical data, and discusses the need to identify new theranostic biomarkers from tissue and fluid biopsies, to go...

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Format:	Buch
Sprache:	eng
Schlagworte:	ablation ACKR3 adjuvant chemokine chemotherapy circulating tumor cells Clinical and internal medicine CMS colon cancer colonic neoplasms colorectal cancer discoidin domain receptor Diseases and disorders dual expression early recurrence epigenetics ERBB2 event free survival extracellular vesicles genome-wide association study HER-2 heterogeneity high-definition single-cell assay liquid biopsy liver metastases lung metastases Lynch Syndrome Medicine and Nursing Mendelian randomization metastasis microenvironment mismatch repair proteins multi-assay n/a Oncology oncosomes PD-L1 polygenic risk scores poor prognosis pre-metastatic niche precision medicine prognosis protein biomarker rare cell RAS mutations resection resistance signaling pathways Snail transcription factor surgery survival therapy tumor budding
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Beschreibung
Zusammenfassung:	Despite major medical advances in recent decades, colorectal cancer remains a major public health problem with significant unmet medical needs. This reprint presents new scientific and clinical data, and discusses the need to identify new theranostic biomarkers from tissue and fluid biopsies, to go further in terms of personalised medicine and thus overcome current limitations.
DOI:	10.3390/books978-3-0365-6836-2