Integrative Multi-Omics in Biomedical Research

Genomics technologies revolutionised biomedicine research, but the genome alone is not sufficient to capture biological complexity. Postgenomic methods, typically based on mass spectrometry, comprise the analysis of metabolites, lipids, and proteins and are an essential complement to genomics and tr...

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Format:	Buch
Sprache:	eng
Schlagworte:	acute myeloid leukemia analysis flow anti-angiogenesis ATRA Barrett’s esophagus batch variations bioinformatics Biology, life sciences Book Industry Communication cardiac metaplasia cGAS cheminformatics curcumin DNA sensing eicosanoids endometriosis esophageal adenocarcinoma exercise fetal calf serum heart HL-60 cell line host-pathogen interactions IFI16 induced differentiation inflammation innate immunity key molecules label-free method for drugs lipid lipidomics machine learning macrophages mass spectrometry Mathematics & science mechanism of action metabolomics microbiota multi-omics multi-omics analysis myocardial infarction (MI) n/a natural products peroxisomes planned myocardial infarction (PMI) post-translational modifications protein interactions proteome proteomics receptor tyrosine kinases Reference, information & interdisciplinary subjects regulatory pathway modelling Research & information: general secretome SRM study design target identification target validation transcription factors transcriptome transcriptomics virus–host interactions
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Beschreibung
Zusammenfassung:	Genomics technologies revolutionised biomedicine research, but the genome alone is not sufficient to capture biological complexity. Postgenomic methods, typically based on mass spectrometry, comprise the analysis of metabolites, lipids, and proteins and are an essential complement to genomics and transcriptomics. Multidimensional omics is becoming established to provide accurate and comprehensive state descriptions. This book covers the latest methodological developments for, and applications of integrative multi-omics in biomedical research.
DOI:	10.3390/books978-3-0365-2583-9