Multiscale Modeling of the Ventricles: From Cellular Electrophysiology to Body Surface Electrocardiograms

Multiscale Modeling of the Ventricles: From Cellular Electrophysiology to Body Surface Electrocardiograms

This work is focused on different aspects within the loop of multiscale modeling:On the cellular level, effects of adrenergic regulation and the Long-QT syndrome have been investigated.On the organ level, a model for the excitation conduction system was developed and the role of electrophysiological...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: Keller, David Urs Josef
Format: Buch
Sprache:eng
Schlagworte:
Cardiac Electrophysiology
Electrophysiological Heterogeneities
Forward Calculation
Multiscale Modeling
T1-995
Technology, Engineering, Agriculture, Industrial processes
Technology: general issues
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Beschreibung
Zusammenfassung:This work is focused on different aspects within the loop of multiscale modeling:On the cellular level, effects of adrenergic regulation and the Long-QT syndrome have been investigated.On the organ level, a model for the excitation conduction system was developed and the role of electrophysiological heterogeneities was analyzed.On the torso level a dynamic model of a deforming heart was created and the effects of tissue conductivities on the solution of the forward problem were evaluated.
ISSN:1864-5933
DOI:10.5445/KSP/1000023886