Correlation between recurrence of anorectal condyloma acuminatum and human papilloma virus subtype

Background Anorectal condyloma is the representative venereal disease caused by human papilloma virus (HPV), which has more 180 subtypes. Although there are various known risk factors for recurrence, few studies have investigated the influence of HPV subtypes. Objective We aimed to investigate the correlation between the recurrence of anorectal condyloma and HPV subtypes. Methods We analyzed the clinical and histopathological information of 143 patients who underwent surgery for anorectal condyloma at the National Medical Center between March 2016 and September 2020. PCR analyses were performed to confirm the HPV subtype in 24 patients. Results Recurrence was confirmed in 63 patients through outpatient follow-up over a median of 31.7 months (range: 0–56.2) after surgery. Recurrence was significantly associated with anorectal condyloma severity ( p