Efficacy of Ultrasound-Guided Core Needle Biopsy in Detecting Metastatic Axillary Lymph Nodes in Breast Cancer
Purpose: Axillary lymph node status is an important prognostic factor in breast cancer. Axillary lymph nodes can be evaluated using fine-needle aspiration cytology (FNAC) or core needle biopsy (CNB) before surgery. This study compared the accuracy and false-negative rates between FNAC and CNB in pat...
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Veröffentlicht in: | Journal of Surgical Ultrasound 2020, 7(2), , pp.21-28 |
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Sprache: | eng |
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Zusammenfassung: | Purpose: Axillary lymph node status is an important prognostic factor in breast cancer. Axillary lymph nodes can be evaluated using fine-needle aspiration cytology (FNAC) or core needle biopsy (CNB) before surgery. This study compared the accuracy and false-negative rates between FNAC and CNB in patients with breast cancer who either did or did not receive neoadjuvant chemotherapy (NAC). Methods : : The clinicopathological factors of the patients were analyzed retrospectively, and the sensitivity, specificity, positive and negative predictive values, false-positive and false-negative rates, and accuracy of FNAC (n = 27) and CNB (n = 23) were compared. Results : : Regardless of whether or not NAC was performed, the CNB evaluation of the metastatic axillary lymph nodes had a 100.0% sensitivity, specificity, negative predictive value, and accuracy, except for one case with an inadequate sample. In the FNAC group, the false-negative rate was higher in patients with breast cancer who received NAC before evaluating the lymph nodes (9.1% vs. 7.7%). Moreover, ultrasound imaging was the most sensitive imaging modality that can detect the suspicious axillary lymph node. Conclusion : : CNB was more effective in evaluating the axillary lymph nodes in breast cancer than FNAC and was performed without major complications. |
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ISSN: | 2288-9140 2671-7883 |
DOI: | 10.46268/jsu.2020.7.2.21 |