Fusobacterium nucleatum: caution with interpreting historical patient sample cohort

[2] published in Journal of Pathology amd Translational Medicine, utilize quantative polymerase chain reaction for the NusG gene in Fn relative to a control prostaglandin transporter gene (SLCO2A1). Historical tumor samples were obtained from tumor banks under the auspices of Institutional Review Board-approved protocols. Yan X, Liu L, Li H, Qin H, Sun Z. Clinical significance of Fusobacterium nucleatum, epithelial-mesenchymal transition, and cancer stem cell markers in stage III/IV colorectal cancer patients. Fusobacterium nucleatum infection correlates with two types of microsatellite alterations in colorectal cancer and triggers DNA damage.