Comparison of proinsulin to C-peptide ratio in children with and without type 1 diabetes and its relation to age
This study aimed to compare the proinsulin to C-peptide (PI:C) ratio in those with recent-onset type 1 diabetes versus those with no diabetes and to explore the effect of age on PI:C ratio. Nineteen participants (n=9 with type 1 diabetes and n=10 with no diabetes) between 10 and 19 years of age were...
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Veröffentlicht in: | Annals of pediatric endocrinology & metabolism 2020, 25(1), , pp.38-41 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | This study aimed to compare the proinsulin to C-peptide (PI:C) ratio in those with recent-onset type 1 diabetes versus those with no diabetes and to explore the effect of age on PI:C ratio.
Nineteen participants (n=9 with type 1 diabetes and n=10 with no diabetes) between 10 and 19 years of age were enrolled in a single-visit cross-sectional study and underwent blood collection after 10 hours fasting to measure proinsulin and C-peptide levels as well as other glycemic parameters.
The median PI:C ratio was significantly different between type 1 diabetes and nondiabetes groups (6.24% vs. 1.46%, P |
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ISSN: | 2287-1012 2287-1292 |
DOI: | 10.6065/apem.2020.25.1.38 |