Determination of Silymarin and Silybin Diastereomers in Korean Milk Thistle using HPLC/UV Analysis

Silymarin (SM) and silybin diastereomers (SD) in milk thistle (Silybum marianum) were determined using high-performance liquid chromatography and quantified using a reverse-phase column in a gradient elution system. UV detection was performed at 288 nm. The content of SM and SD in milk thistle was 3...

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Veröffentlicht in:	생약학회지(Korean Journal of Pharmacognosy) 2020, 51(4), , pp.297-301
Hauptverfasser:	Juree Kim(김주리), Leo Adrianne Paje(레오 아드리안 바헤), Jung Won Choi(최중원), Hak-Dong Lee(이학동), Jae Suk Shim(심재석), Jeehyoung Shim(심지형), Paul John L. Geraldino(폴 존 헤랄디노), Sanghyun Lee(이상현)
Format:	Artikel
Sprache:	eng
Schlagworte:	약학
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Zusammenfassung:	Silymarin (SM) and silybin diastereomers (SD) in milk thistle (Silybum marianum) were determined using high-performance liquid chromatography and quantified using a reverse-phase column in a gradient elution system. UV detection was performed at 288 nm. The content of SM and SD in milk thistle was 3.236 and 0.553 mg/g DW, respectively. Determining the presence and quantifying the content of SM and SD in milk thistle are vital for the pharmaceutical industry to identify optimal sources for developing health supplements or therapeutics. KCI Citation Count: 1
ISSN:	0253-3073 2288-9299
DOI:	10.22889/KJP.2020.51.4.297