Some Monascus purpureus Genomes Lack the Monacolin K Biosynthesis Locus

Two Monascus purpureus genomes lack the monacolin K biosynthesis locus (mok), while Monascus species are generally assumed to be monacolin K producers. These M. purpureus harbor a fusion of mokA and mokB orthologues. This finding suggests that an ancestral mok locus underwent a deletion event in the...

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Veröffentlicht in:Journal of applied biological chemistry 2016, 59(1), , pp.45-47
Hauptverfasser: Kwon, Hyung-Jin, Balakrishnan, Bijinu, Kim, Yeon-Ki
Format: Artikel
Sprache:eng
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Zusammenfassung:Two Monascus purpureus genomes lack the monacolin K biosynthesis locus (mok), while Monascus species are generally assumed to be monacolin K producers. These M. purpureus harbor a fusion of mokA and mokB orthologues. This finding suggests that an ancestral mok locus underwent a deletion event in the M. purpureus genome. KCI Citation Count: 1
ISSN:1976-0442
2234-7941
DOI:10.3839/jabc.2016.009