Cytotoxic Terpenoids from the Methanolic Extract of Bridelia cambodiana

Bioactivity-guided isolation of Bridelia cambodiana, with a cytotoxicity assay using a small panel of cancer cell tines, led to the isolation and identification of five active compounds, 24-methytlanosta-9(11),25-dien-3β-ol, 3-epi-glutinol, betulinic acid, ursolic acid, and maslinic acid, along with...

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Veröffentlicht in:Applied biological chemistry 2009, 52(6), , pp.626-631
Hauptverfasser: Khiev, Piseth, University of Science and Technology, Daejeon, Republic of Korea, Cai, Xing-Fu, Immune Modulator Research Center, Korea Research Institute of Bioscience and Biotechnology, Ochang, Republic of Korea, Chin, Y.W., Immune Modulator Research Center, Korea Research Institute of Bioscience and Biotechnology, Ochang, Republic of Korea, Ahn, K.S., Immune Modulator Research Center, Korea Research Institute of Bioscience and Biotechnology, Ochang, Republic of Korea, Lee, H.K., Immune Modulator Research Center, Korea Research Institute of Bioscience and Biotechnology, Ochang, Republic of Korea, Oh, S.R., Immune Modulator Research Center, Korea Research Institute of Bioscience and Biotechnology, Ochang, Republic of Korea
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Sprache:eng
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Zusammenfassung:Bioactivity-guided isolation of Bridelia cambodiana, with a cytotoxicity assay using a small panel of cancer cell tines, led to the isolation and identification of five active compounds, 24-methytlanosta-9(11),25-dien-3β-ol, 3-epi-glutinol, betulinic acid, ursolic acid, and maslinic acid, along with eight triterpenoids and three steroids.
ISSN:1738-2203
2468-0834
2234-344X
2468-0842
DOI:10.3839/jksabc.2009.104