Outbreaks of Imipenem-Resistant Acinetobacter baumannii Producing Carbapenemases in Korea

Among 53 Acinetobacter baumannii isolates collected in 2004, nine imipenem-resistant isolates were obtained from clinical specimens taken from patients hospitalized in Busan, Korea. Nine carbapenemase-producing isolates were further investigated in order to determine the mechanisms underlying resist...

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Veröffentlicht in:	The journal of microbiology 2006, 44(4), , pp.423-431
Hauptverfasser:	Jeong, S.H. (Kosin University, Busan, Republic of Korea), Bae, I.K. (Kosin University, Busan, Republic of Korea), Park, K.O. (Kosin University, Busan, Republic of Korea), An, Y.J. (Myongji University, Yongin, Republic of Korea), Sohn, S.G. (Myongji University, Yongin, Republic of Korea), Jang, S.J. (Myongji University, Yongin, Republic of Korea), Sung, K.H. (Myongji University, Yongin, Republic of Korea), Yang, K.S. (Myongji University, Yongin, Republic of Korea), Lee, K.W. (Yonsei University, Seoul, Republic of Korea), Young, D.E. (Yonsei University, Seoul, Republic of Korea), Lee, S.H. (Myongji University, Yongin, Republic of Korea), E-mail: sangheelee@mju.ac.kr
Format:	Artikel
Sprache:	eng
Schlagworte:	Acinetobacter baumannii Acinetobacter baumannii - drug effects Acinetobacter baumannii - enzymology Acinetobacter baumannii - isolation & purification Acinetobacter Infections - epidemiology Acinetobacter Infections - microbiology Anti-Bacterial Agents - metabolism Anti-Bacterial Agents - pharmacology BACTERIA GRAM NEGATIVA Bacterial Proteins - metabolism BACTERIE GRAM NEGATIF beta-Lactamases - metabolism carbapenemase Cross Infection - epidemiology Cross Infection - microbiology Disease Outbreaks Drug Resistance, Multiple, Bacterial ERIC-PCR GRAM NEGATIVE BACTERIA Humans Imipenem - metabolism Imipenem - pharmacology IMP-1 Korea - epidemiology OXA-23 Phenotype Polymerase Chain Reaction - methods 생물학
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Zusammenfassung:	Among 53 Acinetobacter baumannii isolates collected in 2004, nine imipenem-resistant isolates were obtained from clinical specimens taken from patients hospitalized in Busan, Korea. Nine carbapenemase-producing isolates were further investigated in order to determine the mechanisms underlying resistance. These isolates were then analyzed via antibiotic susceptibility testing, microbiological tests of carbapenemase activity, pI determination, transconjugation test, enterobacterial repetitive consensus (ERIC)-PCR, and DNA sequencing.
ISSN:	1225-8873 1976-3794