Palladium-Catalyzed Cross-Coupling Reaction and Gold-Catalyzed Cyclization for Preparation of Ethyl 2-Aryl 2,3-Alkadienoates and α-Aryl γ-Butenolides

Palladium-Catalyzed Cross-Coupling Reaction and Gold-Catalyzed Cyclization for Preparation of Ethyl 2-Aryl 2,3-Alkadienoates and α-Aryl γ-Butenolides

Efficient synthetic method for the preparation of ethyl 2-aryl-2,3-alkadienoates through Pd-catalyzed selective allenyl cross-coupling reactions of aryl iodides with organoindiums generated in situ from indium and ethyl 4-bromo-2-alkynoate was developed. The cyclization reaction of ethyl 2-aryl-2,3-...

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Veröffentlicht in:Bulletin of the Korean Chemical Society 2011, 32(8), , pp.2911-2915
Hauptverfasser: Mo, Jun-Tae, Hwang, Hoon, Lee, Phil-Ho
Format: Artikel
Sprache:eng
Schlagworte:
화학
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Zusammenfassung:Efficient synthetic method for the preparation of ethyl 2-aryl-2,3-alkadienoates through Pd-catalyzed selective allenyl cross-coupling reactions of aryl iodides with organoindiums generated in situ from indium and ethyl 4-bromo-2-alkynoate was developed. The cyclization reaction of ethyl 2-aryl-2,3-alkadienoates catalyzed by AuCl_3 and AgOTf in the presence of AcOH or TfOH produced various α-aryl γ-butenolides or γ-substituted α-aryl γ-butenolides. KCI Citation Count: 6
ISSN:0253-2964
1229-5949
DOI:10.5012/bkcs.2011.32.8.2911