Clinical characteristicsofacuterenalfailurewithsevereloinpainandpatchy renal vasoconstriction

Background: Acute renalfailure(ARF)withsevereloinpainandpatchyrenal vasoconstriction (PRV)isasyndromepresentingwithsuddenloinpainafter anaerobic exercise.Weaimedtoinvestigatetheclinicalcharacteristicsandthe efficacy ofdiagnosticimagingstudiesofpatientswiththissyndrome. Methods: We retrospectivelyselected17patientswithARFaccompaniedbyloin or abdominalpainwhoshowedmultiplepatchywedge-shapeddelayedcontrast enhancements onacomputerizedtomographyscan.Informationabouttheclinical characteristics, includingthenatureofpainandcombinedsymptoms,suspected causes, suchasexercise,drugoralcoholintake,andrenalhypouricemia,andthe results oflaboratoryandimagingtestsweregathered. Results: The meanageofpatientswithepisodesofARFaccompaniedbyloinpain was 23.076.5(range16–35)yearsold.Painwasmainly locatedintheloin(70.6%)or abdominalarea(76.5%)andcontinuedforapproximately3.574.0 days.Exercisewas suspectedasaprimarycauseofdiseasein12(70.6%)patients.Maximalserum creatininewas5.4273.16 (1.4–12.1)mg/dL3.171.8 (1–7)daysaftertheonsetof pain.Thepeaklevelofserumuricacidwas9.4172.91 (6.0–15.8)mg/dL.Allofthe patientsrecoveredtonear-normalrenalfunction,andonepatientshowedhypour-icemiaafterrecovery. Conclusion: ARF withsevereloinpainandPRVcanpresentwithloinorabdominal pain,evenwithoutahistoryofanaerobicexercise.Carefulhistorytakingand appropriateimagingstudiesarecriticalinthediagnosisandmanagementofthis syndrome. KCI Citation Count: 0