Synapsin Isoforms and Synaptic Vesicle Trafficking

Synapsins were the first presynaptic proteins identified and have served as the flagship of the presynaptic protein field. Here we review recent studies demonstrating that different members of the synapsin family play different roles at presynaptic terminals employing different types of synaptic ves...

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Veröffentlicht in:Molecules and cells 2015, 38(11), , pp.936-940
Hauptverfasser: Song, S.H., Lee Kong Chian School of Medicine, Singapore, Singapore, Augustine, G.J., Institute of Molecular and Cell Biology, Singapore, Singapore
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Sprache:eng
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Zusammenfassung:Synapsins were the first presynaptic proteins identified and have served as the flagship of the presynaptic protein field. Here we review recent studies demonstrating that different members of the synapsin family play different roles at presynaptic terminals employing different types of synaptic vesicles. The structural underpinnings for these functions are just beginning to be understood and should provide a focus for future efforts.
ISSN:1016-8478
0219-1032
DOI:10.14348/molcells.2015.0233