Effect of a Gluten Free Diet on Hepatitis B Surface Antibody Concentration in Previously Immunized Pediatric Celiac Patients

To evaluate the effect of gluten-free diet (GFD) on hepatitis B surface antibody (HBsAb) concentrations among previously immunized pediatric celiac disease (CD) subjects. We retrospectively evaluated pediatric CD subjects in serological remission who were previously immunized for hepatitis B virus a...

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Veröffentlicht in:Pediatric gastroenterology, hepatology & nutrition 2020, Hepatology & Nutrition, 23(2), , pp.132-136
Hauptverfasser: Zifman, Eyal, Zevit, Noam, Heshin-Bekenstein, Merav, Turner, Dan, Shamir, Raanan, Silbermintz, Ari
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Sprache:eng
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Zusammenfassung:To evaluate the effect of gluten-free diet (GFD) on hepatitis B surface antibody (HBsAb) concentrations among previously immunized pediatric celiac disease (CD) subjects. We retrospectively evaluated pediatric CD subjects in serological remission who were previously immunized for hepatitis B virus as infants. The temporal relationship between HBsAb concentration, the amount of time on a GFD, and age were evaluated. Overall, 373 CD subjects were analyzed: 156 with HBsAb sampled prior to GFD initiation and 217 after initiation of a GFD and in serological remission. Median age at HBsAb concentration measurement for those before and after GFD initiation was 5.3 years (interquartile range [IQR], 3.1-9.2 years) and 7.6 years (IQR, 5.4-10.9 years), respectively (
ISSN:2234-8646
2234-8840
DOI:10.5223/pghn.2020.23.2.132