Effects of 10-week combined training on lipid metabolic regulatory hormones and metabolic syndrome index according to exercise dose in obese male college students

To analyze the effects of 10-week combined training (aerobic and resis-tance exercise) in three groups that were divided according to the total exercise dose per week and elucidate its effects on insulin and leptin (lipid metabolic regulatory hormones) and metabolic syndrome index. We included 24 obese male college students with body mass index ≥25 kg/m2. Each 8 subjects were randomly assigned according to the total exercise dose per week into the 150-, 270-, and 450-min/wk exer-cise groups, which performed 50-, 90-, and 90-min exercise per day for 3, 3, and 5 times a week, respectively. To maintain a constant level of exercise intensity, aerobic exercises were performed while maintaining 60%–70% of the maximal heart rate and resistance exercise at 60%–70% load of the initial 1 repetition maximum; 1 repetition maximum was measured every 2 weeks. Training effects on lipid metabolic regulatory hormones in the blood and metabolic syndrome index according to the total exercise dose/week were analyzed. Insulin and leptin levels de-creased in the 270- and 450-min/wk exercise groups but no significant difference was observed in the 150-min/wk exercise group. Waist cir-cumference showed a significant decrease in all groups, but blood pressure did not change. Fasting blood glucose levels significantly de-creased in the 270- and 450-min/wk exercise groups. Triglyceride and high-density lipoprotein-cholesterol levels significantly decreased in the 450-min/wk exercise group. Combined training with an appropriate total exercise dose may prevent diseases caused by obesity by improv-ing energy expenditure and insulin sensitivity and triggering positive changes in glucose and lipid metabolism.