Structure Characterization of Degradation Products of Drug Candidate HM30571 by UPLC‐QTOF‐MS and In Silico Toxicity Prediction

Structure Characterization of Degradation Products of Drug Candidate HM30571 by UPLC‐QTOF‐MS and In Silico Toxicity Prediction

Procedure of forced degradation study, structure elucidation of degradation products by UPLC‐QTOF‐MS and in silico toxicity prediction.

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Veröffentlicht in:Bulletin of the Korean Chemical Society 2020, 41(1), , pp.92-95
Hauptverfasser: Bang, Hyojeong, Whang, Wankyunn, Bang, Keukchan, Lee, Eunyoung, Kim, Eunyoung, Ahn, Younggil, Suh, Kweehyun
Format: Artikel
Sprache:eng
Schlagworte:
Forced degradation study
High‐resolution mass spectrometry
In silico toxicity
Liquid chromatography/quadrupole time‐of‐flight/mass spectrometry
Stability indicating
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Beschreibung
Zusammenfassung:Procedure of forced degradation study, structure elucidation of degradation products by UPLC‐QTOF‐MS and in silico toxicity prediction.
ISSN:1229-5949
0253-2964
1229-5949
DOI:10.1002/bkcs.11913