비용, 상악동 및 하비갑개 조직의 병리조직학적 소견의 비교
Background and Objectives:The nasal polyp is the most common form of mass lesion in the nose with an unclear etiology and pathogenesis among patients in Asia. Also, the pathological characteristic of nasal polyps in these patients is eosinophil infiltration. These findings, as reported in Asia, are...
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Veröffentlicht in: | Journal of rhinology 2008, 15(1), , pp.30-34 |
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Sprache: | kor |
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Zusammenfassung: | Background and Objectives:The nasal polyp is the most common form of mass lesion in the nose with an unclear
etiology and pathogenesis among patients in Asia. Also, the pathological characteristic of nasal polyps in these patients is
eosinophil infiltration. These findings, as reported in Asia, are distinct from those of the West. Moreover, the role of eosinophil
is recently found to be on the increase even in Asia. So, we investigated the proportion of eosinophil infiltration in the
nasal polyp among patients in Korea. Materials and Methods:The study group consisted of 35 patients with a mean age of
43 years (ranging from 6 to 72 years). Tissue samples were taken via endoscopic sinus surgeries from the nasal polyp, inflammatory
sinus mucosa, and the inferior turbinate. We compared 5 parameters of mucosal histopathology. Result:The incidence
of a severe eosinophilic infiltration in the nasal polyp was 70%. Nasal polyp and inflammatory sinus mucosa had a
larger eosinophil, lymphocyte and polymorphonuclear leukocyte infiltration than a normal nasal mucosa. Also, the nasal polyp
and sinus mucosa had a more severe basement membrane thickening and goblet cell hyperplasia. Distinctively, the nasal
polyp had a severe eosinophilic infiltration and a more thickened basement membrane. Conclusion:The present histopathologic
feature of the nasal polyp among Koreans indicates that cases of eosinophilic nasal polyp seems to be on the increase. KCI Citation Count: 0 |
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ISSN: | 1229-1498 2384-4361 |