Enzyme Gel 법에서 항체 반응이 소실된 항-Jka 1예

저자들은 효소법에서 항체 반응이 소실된 항- Jka 1예를 경험하였기에 이를 보고하는 바이다. 환자는 56세 여자로 발열과 근육통 및 오심, 구토를 주소로 내원하였다. LISS/Coombs gel card법을 이용한 항체선별검사 및 동정검사(DiaMed AG, Cressier sur Morat, Switzwerland)에서 항-Jka가 동정되었고 반응 강도가 약하여(trace ∼ 1+) 보다 정확한 동정을 위해 Enzyme card법을 추가 시행하였으나 오히려 모든 panel cell과의 반응이 음성이었다. Kidd 표현형은 Jk(a-b+)이었다. 복부단층촬영에서 6×7.5 cm 크기의 간농양이 관찰되어 경피카테터배액술을 시행받았으며, 이후 증세가 호전되어 내원 23일째 퇴원하였다. We report a case of anti-Jka, whose reactivity was abolished in an enzyme gel test. A 56-year-old woman was admitted to our hospital because of fever, myalgia, nausea and vomiting. Anti-Jka was detected by antibody screening and an identification test using a LISS/Coombs gel card (DiaMed AG, Cressier sur Morat, Switzwerland). Its reactivity was so weak (trace ∼ 1+) that an Enzyme gel card (DiaMed AG) was added to enhance the reactivity. Unexpectedly, all reactions with the enzyme-treated cells showed negative results. The patient’s RBC phenotype was Jk(a-b+). The abdominal CT revealed a 6×7.5 cm sized liver abscess. Her condition improved after percutaneous catheter drainage and she was discharged on the 23rd hospital day. KCI Citation Count: 2