Etiology of Adolescent Idiopathic Scoliosis: A Literature Review

Adolescent idiopathic scoliosis (AIS) is the peripubertal development of spinal curvature of a minimum of 10°. AIS is thought to be attributable to genetic factors, nutrition, early exposure to toxins, and hormonal dysregulation. Recent literature suggests these factors may compound to determine bot...

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Veröffentlicht in:Asian spine journal 2019, 13(3), , pp.519-526
Hauptverfasser: Kikanloo, Sina Rashidi, Tarpada, Sandip Parshottam, Cho, Woojin
Format: Artikel
Sprache:eng
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Zusammenfassung:Adolescent idiopathic scoliosis (AIS) is the peripubertal development of spinal curvature of a minimum of 10°. AIS is thought to be attributable to genetic factors, nutrition, early exposure to toxins, and hormonal dysregulation. Recent literature suggests these factors may compound to determine both disease onset and severity. Currently, treatment is limited to observation, bracing, and surgical intervention. Intervention is presently determined by severity and risk of curve progression. As they emerge, new therapies may target specific etiologies of AIS.
ISSN:1976-1902
1976-7846
DOI:10.31616/asj.2018.0096