手少陽三焦經 正格의 自經補瀉(中渚 補, 液門 瀉) 刺鍼이 정상 흰쥐의 腦血流量 및 血壓에 미치는 影響

Objectives : Joongjeo(TE3) Supplementation Aekmoon(TE2) Draining is a method belongs to Ohaeng-acupuncture, using directional supplementation and draining. Methods : This study was designed to investigate the effects of TE3 supplementation TE2 draining on changes in cerebral blood flow (rCBF) and mean arterial blood pressure (MABP) in normal rats. For these reasons, the present author investigated rCBF and MABP using laser doppler flowmeter in normal rats. In addtion, the present author also investigated action mechanisms of TE3 supplementation TE2 draining on changes in rCBF and MABP too. Results : In this results, TE3 supplementation TE2 draining elevated rCBF in time-dependent manner, but MABP levels decresed by TE3 supplementation TE2 draining. Pre-treatment with indomethacin (IDM), an inhibitor of cyclooxygenase, inhibited increase of rCBF effectively. But pre-treatment with methylene blue (MTB), an inhibitor of guanylate cyclase, decreased rCBF levels. In addition, pre-treatment with IDM also decreased MABP levels, but pre-treatement with MTB increased MABP levels. Conclusions : In conclusion, these results suggest that TE3 supplementation TE2 draining is effective to treat patient with disease related to cerebral ischemia, because TE3 supplementation TE2 draining can increase rCBF. In addition, the mechanisms are thought to be related to guanylate cyclase pathways. Objectives : Joongjeo(TE3) Supplementation Aekmoon(TE2) Draining is a method belongs to Ohaeng-acupuncture, using directional supplementation and draining. Methods : This study was designed to investigate the effects of TE3 supplementation TE2 draining on changes in cerebral blood flow (rCBF) and mean arterial blood pressure (MABP) in normal rats. For these reasons, the present author investigated rCBF and MABP using laser doppler flowmeter in normal rats. In addtion, the present author also investigated action mechanisms of TE3 supplementation TE2 draining on changes in rCBF and MABP too. Results : In this results, TE3 supplementation TE2 draining elevated rCBF in time-dependent manner, but MABP levels decresed by TE3 supplementation TE2 draining. Pre-treatment with indomethacin (IDM), an inhibitor of cyclooxygenase, inhibited increase of rCBF effectively. But pre-treatment with methylene blue (MTB), an inhibitor of guanylate cyclase, decreased rCBF levels. In addition, pre-treatment with IDM also decreased MABP levels, but pre-treatement with MTB increased MABP levels. Conclusions : In