Te Overlap between Fibromyalgia Syndrome and Myotonia Congenita

Background Fibromyalgia syndrome (FMS) is a complex disorder characterized by chronic widespread pain (CWP), multiple areas of tenderness, sleep disturbance, fatigue, andmood or cognitive dysfunction. Myotonia congenita (MC) is an inherited myopathic disorder that is caused by mutations in the gene encoding the skeletal muscle chloride channel,which can infrequently manifest as generalized muscle cramps or myalgia. Case Report Te frst case was a 33-year-old woman who complained of CWP and chronic headache occurring during pregnancy, and the second case was a 37-year-old man withCWP and depression who sufered from cold-induced muscle cramps. Tese two patientswere initially diagnosed with FMS by rheumatologists, based on CWP of longer than 3months duration and mechanical tenderness in specifc body regions. However, these twoFMS patients were subsequently also diagnosed with MC. Conclusions Tese two cases are the frst report of an overlap of CWP between FMS and MC. KCI Citation Count: 3