Phytochemical Constituents of Schizonepeta tenuifolia Briquet

Column chromatographic separation of the MeOH extract from the aerial parts of Schizonepeta tenuifolia Briquet led to the isolation of twelve terpenes (1 - 11 and 17), four phenolics (13 - 16) and a hexenyl glucoside (12). Their structures were determined by spectroscopic means to be (−)-pulegone (1), piperitenone (2), p-cymene-3,8-diol (3), schizonepetoside A (4), schizonepetoside C (5), (+)-spatulenol (6), ursolic acid (7), 2α,3α,24α,-trihydroxyolean-12en-28oic acid (8), 5α,8α-epidioxyergosta-6,22-diol-3β-ol (9), stigmast-4-en-3-one (10), β-sitosterol (11), (Z)-3-hexenyl-1-O-β-D-glucopyranoside (12), rosmarinic acid (13), apigenin-7-O-β-Dglucopyranoside (14), luteolin-7-O-β-D-glucuronopyranoside (15), hesperidin (16) and trans-phytol (17). Compounds 2, 3, 8, 9 and 12 were for the first time isolated from S. tenuifolia Briq. KCI Citation Count: 3