A New Antioxidant from the Marine Sponge-derived Fungus Aspergillus versicolor

A chemical investigation of the marine-derived fungi Aspergillus versicolor led to the isolation of a new aromatic polyketide (1), The structure was elucidated by spectroscopic analysis, and its radical-scavenging activity, reducing power, and inhibitory activity to lipid oxidation were investigated...

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Veröffentlicht in:	Natural product sciences 2011, 17(1), , pp.14-18
Hauptverfasser:	Li, Jian Lin, Pusan National University, Busan, Republic of Korea, Lee, Y.M., Pusan National University, Busan, Republic of Korea, Hong, J.K., Kyung Hee University, Seoul, Republic of Korea, Bae, K.S., Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea, Choi, J.S., Pukyong National University, Busan, Republic of Korea, Jung, J.H., Pusan National University, Busan, Republic of Korea
Format:	Artikel
Sprache:	eng
Schlagworte:	ANTIOXIDANTES ANTIOXIDANTS ANTIOXYDANT aromatic polyketide ASPERGILLUS VERSICOLOR marine fungus 약학
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Zusammenfassung:	A chemical investigation of the marine-derived fungi Aspergillus versicolor led to the isolation of a new aromatic polyketide (1), The structure was elucidated by spectroscopic analysis, and its radical-scavenging activity, reducing power, and inhibitory activity to lipid oxidation were investigated. Those activities of compound 1 were compared with standard antioxidants such as butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT), tertiarybutylhydroquinone (TBHQ), and ascorbic acid (V∧C). Compound 1 showed antioxidant activity comparable to that of BHA, and siginificantly higher than that of BHT.
ISSN:	1226-3907 2288-9027