오미자 효소가수분해물에 의한 장내 세균총 개선 및장관 염증 억제 효과의 효소학적 평가

Fruits has been used as a traditional Oriental medicine for treatment of many stress-induced diseases.Schizandrae fructus (SC-EX) in growthof tested intestinal microorganism and activity of bowel inflammation related enzyme. SC-EX was added to the proteose pep-tone-yeast extract-fildes (PYF) media to investigation the effect on the growth of type culture of intestinal microorganism. Thegrowth of lactic acid bacteria such as Bifidobacterium species and Lactobacillus species was accelerated by more than 3% con-centration of SC-EX. But, growth of harmfulness bacteria such as E.coli, Clostridium sp. Staphylococcus sp. Streptococcus sp.was inhibited by more than 3% concentration of SC-EX. Also, SC-EX was exhibited a concentration-dependent inhibitoryactivity of the bowel inflammation related enzymes. The SC-EX was showed 76% and 92% inhibitory activity of 5-lipoxy-genase and cyclooygenase at 5% additional concentration respectively. Our results indicated that SC-EX may possess improve-Key wordsSchizandrae fructus, intestinal microbial flora, enzymological evaluation... ... .. ... 400. ... ... .. KCI Citation Count: 6