Preventative activity of kimchi on high cholesterol diet-induced hepatic damage through regulation of lipid metabolism in LDL receptor knockout mice

This study investigated the effect of kimchi on hepatic lipid metabolism and inflammatory response. Low-density lipoprotein receptor knockout mice fed high cholesterol diet (HCD) with an oral administration of kimchi methanol extracts (KME, 200 mg kg bw −1 day −1 ) or distilled water for 8 weeks (n...

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Veröffentlicht in:	Food science and biotechnology 2018, 27(1), , pp.211-218
Hauptverfasser:	Woo, Minji, Kim, Mijeong, Noh, Jeong Sook, Park, Chan Hum, Song, Yeong Ok
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry Chemistry and Materials Science Cholesterol Cytokines Damage prevention Diet Distilled water Excretion Fatty acids Fatty liver Food Science High cholesterol diet Inflammation Inflammatory response Kimchi Lipid metabolism Lipids Liver Low density lipoprotein Metabolism Mice Nutrition Oils & fats Oral administration Oxidation Receptor density Rodents Synthesis 식품과학
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Zusammenfassung:	This study investigated the effect of kimchi on hepatic lipid metabolism and inflammatory response. Low-density lipoprotein receptor knockout mice fed high cholesterol diet (HCD) with an oral administration of kimchi methanol extracts (KME, 200 mg kg bw −1 day −1 ) or distilled water for 8 weeks (n = 10 per group). Compared with the control group, plasma and hepatic lipid concentrations were lower in the kimchi group ( p
ISSN:	1226-7708 2092-6456
DOI:	10.1007/s10068-017-0202-3