LC-QTOF-MS를 활용한 현미 중 동물용의약품의 정량 분석
SPE cartridge clean-up method for simultaneous determination of veterinary pharmaceuticals (VPs) in brown rice was developed and validated by LC-QTOF-MS. The clean-up method was established with HLB (500 mg, 6 mL) cartridges for VPs in brown rice, and the eluate was analyzed to quantify the compound...
Gespeichert in:
Veröffentlicht in: | 농약과학회지 2017, 21(3), , pp.269-278 |
---|---|
Hauptverfasser: | , , , , , , , , , |
Format: | Artikel |
Sprache: | kor |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
Zusammenfassung: | SPE cartridge clean-up method for simultaneous determination of veterinary pharmaceuticals (VPs) in brown rice was developed and validated by LC-QTOF-MS. The clean-up method was established with HLB (500 mg, 6 mL) cartridges for VPs in brown rice, and the eluate was analyzed to quantify the compounds by LC-QTOF-MS. The developed method was validated, and the recovery, RSD, and LOQ of VPs were 70.3-112.0%, 1.1-5.7%, and $0.076-7.6{\mu}g/kg$, respectively. These results showed that the developed method for simultaneous determination of VPs contribute to monitoring of it in agricultural environment and agriculture product. 본 연구는 LC-QTOF-MS를 활용하여 현미 중 동물용의약품 분석을 위한 SPE cartridge 정제방법 및 다성분 동시분석법을 개발하고자 하였다. 현미 중 동물용의약품 분석을 위한 정제 방법은 HLB cartridge (500 mg, 6 mL)를 사용하였고, 그 용리액을 LC-QTOF-MS로 분석하였다. 개발된 분석방법의 유효성은 회수율, RSD 및 LOQ로 검증하였으며, 그 값은 각각 70.3-112.0%, 1.1-5.7% 및 $0.076-7.6{\mu}g/kg$ 이었다. 본 연구에서 개발된 동물용의약품 동시분석법은 농업환경 및 농산물 중 이들의 모니터링에 활용될 수 있을 것으로 판단된다. |
---|---|
ISSN: | 1226-6183 2287-2051 |
DOI: | 10.7585/kjps.2017.21.3.269 |