Predictive Factors for Recurrence after Burr-Hole Craniostomy of Chronic Subdural Hematoma

Chronic subdural hematoma is a common and relatively benign disease. However, recurrence is common after surgical treatment, and the recurrence rate varies from 5% to 33%. The aim of this study was to investigate the predictive factors for recurrence of chronic subdural hematoma. We analyzed data from 248 patients with chronic subdural hematoma who were treated by burr-hole craniostomy with a closed drainage system for hematoma evacuation in this five-year retrospective study. Thirty-one (12.6%) patients underwent re-operation for recurrence of chronic subdural hematoma. Univariate analysis revealed that anticoagulation ( =0.0279), headache ( =0.0323), and preoperative midline shifting ( =0.0321) showed significant differences with respect to recurrent chronic subdural hematoma. We performed a multivariate logistic regression analysis and found that diabetes mellitus (odds ratio [OR], 2.618; 95% confidence interval [CI], 1.0899-6.2898; =0.0314), anticoagulation (OR, 6.739; 95% CI, 1.1287-40.2369; =0.0364), headache (OR, 2.951; 95% CI, 1.1464-7.5964; =0.0249), and preoperative midline shifting (OR, 1.0838; 95% CI, 1.0040-1.1699; =0.0391) were independent predictive factors for recurrence of chronic subdural hematoma. We showed that diabetes mellitus, anticoagulation, headache, and preoperative midline shifting were independent predictors of recurrence of chronic subdural hematoma.