다이셀레닐네이션을 이용한 알킬설포닐기가 치환된 새로운 다이피리다지닐 다이셀레나이드의 형성반응
A new series of bis (pyridazinyl) diselenides was synthesized by diselenylation from pyridazinyl chloride forsearch of antiproliferative agents. The process involves the alkylthiolation, oxidation (sulfonylation and sulfinylation) anddiselenylation from 3,6-dichloropyridazine. The alkylsulfonyl (or...
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| Veröffentlicht in: | Yaghag-hoi-ji 2017, 61(4), , pp.222-226 |
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| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | kor |
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| Online-Zugang: | Volltext |
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| Zusammenfassung: | A new series of bis (pyridazinyl) diselenides was synthesized by diselenylation from pyridazinyl chloride forsearch of antiproliferative agents. The process involves the alkylthiolation, oxidation (sulfonylation and sulfinylation) anddiselenylation from 3,6-dichloropyridazine. The alkylsulfonyl (or sulfinyl) pyridazinyl chloride (3c, 4a~4f) could be convertedto target diorganodiselenides 5c, and 6a~6f with selenium, hydrazine hydrate under atmospheric pressure in thepresence of sodium hydroxide. The structures of the synthetic compounds were characterized using 1H and 13C NMR spectroscopy. KCI Citation Count: 0 |
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| ISSN: | 0377-9556 2383-9457 |