Expression of Human Interleukin-11 and Granulocyte-Macrophage Colony-Stimulating Factor in Transgenic Plants

Expression of Human Interleukin-11 and Granulocyte-Macrophage Colony-Stimulating Factor in Transgenic Plants

The production of therapeutic proteins for human diseases in plants results in many economic benefits, including reduced risk of animal virus contamination, high yields, and reduced production and storage costs. Human cytokines, interleukin-11 (hIL-11) and granulocyte-macrophage colony-stimulating f...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of microbiology and biotechnology 2005, 15(6), , pp.1304-1309
Hauptverfasser: Lee, B.Y. (Korea University, Seoul, Republic of Korea), Lee, J.H. (Korea University, Seoul, Republic of Korea), Yoon, H.S. (Korea University, Seoul, Republic of Korea), Kang, K.H. (National Institute of Crop Science, RDA, Suwon, Republic of Korea), Kim, K.N. (Sejong University, Seoul, Republic of Korea), Kim, J.H. (Korea University, Seoul, Republic of Korea), Kim, J.K. (Myongji University, Yongin, Republic of Korea), Kim, J.K. (Korea University, Seoul, Republic of Korea), E-mail: jkkim@korea.ac.kr
Format: Artikel
Sprache:eng
Schlagworte:
ARROZ
Biological and medical sciences
Biotechnology
Fundamental and applied biological sciences. Psychology
GM-CSF
Human cytokines
interleukin-11
PLANTAS TRANSGENICAS
PLANTE TRANSGENIQUE
RICE
RIZ
TABAC
TABACO
TOBACCO
TRANSGENIC PLANTS
생물학
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The production of therapeutic proteins for human diseases in plants results in many economic benefits, including reduced risk of animal virus contamination, high yields, and reduced production and storage costs. Human cytokines, interleukin-11 (hIL-11) and granulocyte-macrophage colony-stimulating factor (hGM-CSF), cDNAs were introduced into rice or tobacco, using either the maize ubiquitin promoter or the 35S promoter. The primary hIL-11 transgenic rice plants exhibited stunted growth and a sterile phenotype, whereas the hIL-11 transgenic tobacco plants did not.
ISSN:1017-7825