A case of isolated lymphoblastic relapse of the central nervous system in a patient with chronic myelogenous leukemia treated with imatinib

Isolated central nervous system (CNS) relapse is a rare, unpre- dictable event in patients with CML. Some studies have reported cases of isolated CNS relapse in CML [1-13]. However, very few studies have reported on isolated CNS relapse in the blast phase (BP) of CML in Korea [14, 15]. We report a c...

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Veröffentlicht in:	Annals of laboratory medicine 2014, 34(3), , pp.247-251
Hauptverfasser:	Park, Mi-Jung, Park, Pil-Whan, Seo, Yiel-Hea, Kim, Kyung-Hee, Seo, Ja-Young, Jeong, Ji-Hun, Kim, Moon Jin, Jeong, Jin-Woo, Ahn, Jeong-Yeal, Park, Jinny
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - therapeutic use Benzamides - therapeutic use Central Nervous System Neoplasms - diagnosis Fusion Proteins, bcr-abl - genetics Humans Imatinib Mesylate Letter to the Editor Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy Leukocytes - metabolism Leukocytes - pathology Male Middle Aged Neoplasm Recurrence, Local Piperazines - therapeutic use Pyrimidines - therapeutic use 병리학
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Zusammenfassung:	Isolated central nervous system (CNS) relapse is a rare, unpre- dictable event in patients with CML. Some studies have reported cases of isolated CNS relapse in CML [1-13]. However, very few studies have reported on isolated CNS relapse in the blast phase (BP) of CML in Korea [14, 15]. We report a case of BP CML with extramedullary lymphoblast proliferation in the CNS without evidence of disease in the peripheral blood (PB) and bone marrow (BM). KCI Citation Count: 3
ISSN:	2234-3806 2234-3814
DOI:	10.3343/alm.2014.34.3.247