수술 후 대장암 환자의 재원기간 운동중재 효과검증: Pilot Randomized Controlled Trial (RCT) Study

Purpose: The purpose of this study was to examine the effect of post-operative exercise on body composition, psychological factors, time to flatus and length of hospital stay in stage 1~3 colorectal cancer patients. Methods: A total of 35 post surgery patients were recruited and randomly assigned to the exercise or controlled group. Participants in the exercise group exercised twice a day while participants in the control group followed the clinical pathways (CP). Results: A total of 25 participants completed the trial. Post-operative exercise resulted in a clinically meaningful, but statistically insignificant reduction in body weight (Exercise: $-1.10{\pm}1.63kg$ vs. CP: $-0.63{\pm}1.16kg$; p=.111), fat mass (Exercise: $-1.43{\pm}0.95kg$ vs. CP: $0.64{\pm}4.29kg$; p=.100). When participants' body composition were compared to their baseline values at the baseline, only the exercise group experienced a significant reduction in body weight, body mass index (BMI) and fat mass. In addition, post-operative exercise significantly improved health related quality of life (Exercise: $2.27{\pm}2.08$ vs CP: $-12.82{\pm}22.47$; p=.008). However, there was no difference in time to flatus and the length of hospital stay between groups. Conclusion: The current pilot study suggests that the post-operative exercise program was safe and produced for health related quality of life improvements in colorectal cancer patients.