수종 인공타액의 초기인공우식 법랑질 재광화 효과에 대한 비교연구

Objectives: The purpose of this study was to compare enamel remineralization effects of human whole saliva and currently available artificial saliva compositions, using teeth exposed to chemical pH cycling conditions, and to obtain data that can inform future design and manufacturing of additional artificial saliva compositions. Methods: Seventy-two specimens of bovine tooth enamel were embedded in resin, then polished and exposed to a lactate/carbopol buffer system for 48-52 hours. Specimens were allocated into six experimental groups (n=12 specimens per group) by randomized blocks, such that each group contained an equivalent proportion of specimens at each Vickers hardness number (VHN) stratum: deionized water as a negative control, human whole saliva and artificial saliva compositions A, B, C and D. Surface hardness was measured before and after 15 days of chemical pH cycling. Surface microhardness was measured (Fm-7, Future-tech Corp, Japan) before and after treatment with test saliva compositions. Oneway ANOVA, with post hoc Tukey test, was used to evaluate statistical differences with a significance threshold of P