Dysregulation of MicroRNA-196b-5p and MicroRNA-375 in Gastric Cancer

Dysregulated microRNAs (miRNAs) can contribute to cancer development by leading to abnormal proliferation of cells, apoptosis, and differentiation. Although several miRNAs that are related to gastric cancer have been identified, the reported results have been inconsistent. The aim of this study was...

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Veröffentlicht in:	Journal of gastric cancer 2016, 16(4), , pp.221-229
Hauptverfasser:	Lee, Seung Woo, Park, Ki Cheol, Kim, Jeong Goo, Moon, Sung Jin, Kang, Sang Bum, Lee, Dong Soo, Sul, Hae Joung, Ji, Jeong Seon, Jeong, Hyun Yong
Format:	Artikel
Sprache:	eng
Schlagworte:	Original 일반외과학
Online-Zugang:	Volltext
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Zusammenfassung:	Dysregulated microRNAs (miRNAs) can contribute to cancer development by leading to abnormal proliferation of cells, apoptosis, and differentiation. Although several miRNAs that are related to gastric cancer have been identified, the reported results have been inconsistent. The aim of this study was to determine miRNA expression profiles and validate miRNAs up- and down-regulated in gastric cancer. We evaluated 34 primary gastric cancer tissues and paired adjacent nontumorous gastric tissues. Total RNA was extracted, and low-molecular-weight RNAs (
ISSN:	2093-582X 2093-5641
DOI:	10.5230/jgc.2016.16.4.221