댕댕이나무(Lonicera coerulea var. edulis) 열매의 항염증 효과 연구

댕댕이나무(Lonicera coerulea var. edulis) 열매의 항염증 효과 연구

In this study, we demonstrated the anti-inflammatory activities of two kinds of blue honeysuckle (Lonicera caerulea var. edulis Turcz, Lonicera caerulea var. longibracteata f. ovata Hara) extracts in the LPS-stimulated macrophages. These two extracts showed non-cytotoxic activity, even at the high c...

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Veröffentlicht in:Yaghag-hoi-ji 2016, 60(5), , pp.235-242
Hauptverfasser: 김정화(Jeong Hwa Kim), 조미나(Mi-na Jo), 한주환(Ju Hwan Han), 표승현(Seung Hyeon Pyo), 김태수(Tae Soo Kim), 김은희(Eun Hee Kim), 이재권(Jae Kwon Lee)
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Sprache:kor
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약학
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Zusammenfassung:In this study, we demonstrated the anti-inflammatory activities of two kinds of blue honeysuckle (Lonicera caerulea var. edulis Turcz, Lonicera caerulea var. longibracteata f. ovata Hara) extracts in the LPS-stimulated macrophages. These two extracts showed non-cytotoxic activity, even at the high concentration. These two extracts of honeysuckle reduced the production of nitric oxide, cyclooxigenase-2 and pro-inflammatory cytokines. The inhibitory activities of two extracts of honeysuckle were found to be caused by blockage of $NF-{\kappa}B$ activation.
ISSN:0377-9556
2383-9457