Ameliorating Effects of a Nopal (Opuntia ficus-indica) Complex on Blood Glucose in db/db Mice

Ameliorating Effects of a Nopal (Opuntia ficus-indica) Complex on Blood Glucose in db/db Mice

This study investigated the effects of a nopal (Opuntia ficus-indica) complex (OF) on blood glucose metabolism in db/db mice for 4 weeks. Food and water intake significantly decreased in OF-treated mice compared to controls (p less than 0.05). In addition, blood glucose and plasma insulin levels wer...

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Veröffentlicht in:Food science and biotechnology 2011, 20(1), , pp.255-259
Hauptverfasser: Yoon, J.A., Baewha Women's University, Seoul, Republic of Korea, Lee, S.J., Korea University, Seoul, Republic of Korea, Kim, H.K., Korea University Guro Hospital, The Korea Lung Tissue Bank, Seoul, Republic of Korea, Son, Y.S., Korea University, Seoul, Republic of Korea
Format: Artikel
Sprache:eng
Schlagworte:
Chemistry
Chemistry and Materials Science
Food Science
hypoglycemic
INSULIN
INSULINA
INSULINE
Nutrition
Opuntia ficus-indica
pancreatic islet
Research Note
식품과학
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Zusammenfassung:This study investigated the effects of a nopal (Opuntia ficus-indica) complex (OF) on blood glucose metabolism in db/db mice for 4 weeks. Food and water intake significantly decreased in OF-treated mice compared to controls (p less than 0.05). In addition, blood glucose and plasma insulin levels were significantly reduced in the OF-treated group compared to the controls (p less than 0.05). Histopathological analysis showed that the morphology of pancreatic islets was improved in the OF-treated db/db mice. Immunohistochemistry of the pancreatic islets showed that insulin production and the number of β-cells apparently increased.
ISSN:1226-7708
2092-6456
DOI:10.1007/s10068-011-0035-4