Effect of Far Infrared Drying on Antioxidant Property, Anti-inflammatory Activity, and Inhibitory Activity in A549 Cells of Gamguk (Chrysanthemum indicum L.) Flower

This research demonstrated and compared the effects of shade and far infrared drying (FIRD) of gamguk (Chrysanthemum indicum L., CE) flowers extract on total phenolic (TP), total flavonoid (TF) content, anticancer and anti-inflammatory activities. The research data revealed that the TP and TF conten...

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Veröffentlicht in:	Food science and biotechnology 2012, 21(1), , pp.261-265
Hauptverfasser:	Kim, W.W., Kangwon National University, Chuncheon, Republic of Korea, Ghimeray, Amal Kumar, Kangwon National University, Chuncheon, Republic of Korea, Wu, J.C., Kangwon National University, Chuncheon, Republic of Korea, Eom, S.H., Kyung Hee University, Yongin, Republic of Korea, Lee, B.G., Korea Energy Technology, Seoul, Republic of Korea, Kang, W.S., Kangwon National University, Chuncheon, Republic of Korea, Cho, D.H., Kangwon National University, Chuncheon, Republic of Korea
Format:	Artikel
Sprache:	eng
Schlagworte:	A549 anti-inflammatory Antiinflammatory agents Antioxidants Antitumor activity Cell proliferation Chemistry Chemistry and Materials Science Chrysanthemum Data processing Drying far infrared ray Flavonoids Flowers Food Science gamguk Lipopolysaccharides Lung cancer Nitric oxide Nutrition phenolic compounds POLIFENOLES POLYPHENOL POLYPHENOLS Prostaglandin E2 Prostaglandin-endoperoxide synthase Research Note Shade Tumors 식품과학
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Zusammenfassung:	This research demonstrated and compared the effects of shade and far infrared drying (FIRD) of gamguk (Chrysanthemum indicum L., CE) flowers extract on total phenolic (TP), total flavonoid (TF) content, anticancer and anti-inflammatory activities. The research data revealed that the TP and TF contents were highest in FIRD treated CE flower extracts. Similarly, the effect of CE on lipopolysaccharide (LPS) induced nitric oxide (NO) production in RAW264.7 cells showed in a dose dependent manner. Further, the CE inhibited the tumor necorsis factor (TNF)-α, cyclooxygenase (COX)-2 expression, and prostaglandis E₂ (PGE₂) production. The anticancer activity was monitored in A549 lung cancer cell, which showed that FIRD treated CE inhibited cell proliferation significantly (p less than 0.05) higher in dose and time dependent manner.
ISSN:	1226-7708 2092-6456
DOI:	10.1007/s10068-012-0034-0