Formation of central cleavage products from lycopene analogues under liposomal suspension

The decrease of lycopene analogues (60 μM) and the formation of its central cleavage products were quantitatively evaluated during the course of autoxidation at 37℃ for 72 h in liposomal suspension. The amounts of central cleavage as carbonyl compounds, acycloretinal, phytofluenal (from ζ-carotene), and phytofluenal (from phytofluene), reached maxima of 36.7, 26.5, and 23.6 nM after 48 h incubation, respectively, while carboxyl cleavage, acycloretinoic acid, 4,5-didehydrogeranyl geranoic acid (from ζ-carotene), and 4,5-didehydrogeranyl geranoic acid (from phytofluene) were reached to 4.6, 3.8, and 3.3 nM at 48 h incubation.