Protective effect of butanol extracts of skin of Anguilla japonica against endoplasmic reticulum stress-induced insulin resistance via the AMPK pathway in L6 myotubes

Protective effect of butanol extracts of skin of Anguilla japonica against endoplasmic reticulum stress-induced insulin resistance via the AMPK pathway in L6 myotubes

The effect of butanol extracts of the skin of Anguilla japonica (BESA) on endoplasmic reticulum (ER) stress-induced insulin resistance in L6 myotubes was investigated. Western blotting revealed that BESA increased phosphorylation of AMP-activated protein kinase (AMPK) and acetyl-CoA carboxylase, and...

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Veröffentlicht in:Food science and biotechnology 2015, 24(3), , pp.1069-1075
Hauptverfasser: Na, Min Kyun, Jeong, Yong-Tae, Li, Xian, Jin, Fansi, Hwang, Seung-Lark, Kim, Geum Jin, Yang, Ju Hye, Chang, Young-Chae, Kim, Dong Soo, Kim, Cheorl-Ho, Chang, Hyeun Wook
Format: Artikel
Sprache:eng
Schlagworte:
Chemistry
Chemistry and Materials Science
Food Science
Nutrition
Research Article
식품과학
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Zusammenfassung:The effect of butanol extracts of the skin of Anguilla japonica (BESA) on endoplasmic reticulum (ER) stress-induced insulin resistance in L6 myotubes was investigated. Western blotting revealed that BESA increased phosphorylation of AMP-activated protein kinase (AMPK) and acetyl-CoA carboxylase, and stimulated glucose uptake in L6 myotubes. Stimulation of AMPK and glucose uptake by BESA were significantly ( p
ISSN:1226-7708
2092-6456
DOI:10.1007/s10068-015-0137-5