Anti-inflammatory effects of flavonoids in Korean Chrysanthemum species via suppression of inducible nitric oxide synthase and cyclooxygenase-2 in LPS-induced RAW 264.7 macrophages

Anti-inflammatory effects of flavonoids in Korean Chrysanthemum species via suppression of inducible nitric oxide synthase and cyclooxygenase-2 in LPS-induced RAW 264.7 macrophages

This study was conducted to compare flavonoids and anti-inflammatory effects in Korean Chrysanthemum species. Leaf samples were identified using HPLC/MS with five flavonoids: luteolin-7- O -rutinoside, luteolin-7- O glucoside, apigenin-7- O -glucoside, apigenin, and acacetin-7- O -rutinoside. Leaf e...

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Veröffentlicht in:Food science and biotechnology 2015, 24(3), , pp.975-985
Hauptverfasser: Kim, Su Jeong, Lee, Kyung-Tae, Choi, Hye-Eun, Ha, Tae Joung, Nam, Jung Hwan, Hong, Su Young, Chang, Dong Chil, Kim, Ki Sun
Format: Artikel
Sprache:eng
Schlagworte:
Chemistry
Chemistry and Materials Science
Food Science
Nutrition
Research Article
식품과학
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Zusammenfassung:This study was conducted to compare flavonoids and anti-inflammatory effects in Korean Chrysanthemum species. Leaf samples were identified using HPLC/MS with five flavonoids: luteolin-7- O -rutinoside, luteolin-7- O glucoside, apigenin-7- O -glucoside, apigenin, and acacetin-7- O -rutinoside. Leaf extracts from four taxa dose-dependently suppressed LPS-stimulated NO production significantly ( p
ISSN:1226-7708
2092-6456
DOI:10.1007/s10068-015-0125-9