Comparison of bioactive compound contents and in vitro and ex vivo antioxidative activities between peel and flesh of pear (Pyrus pyrifolia Nakai)

We compared chemical constituents and antioxidative activities between the flesh and peel of two Asian pears ( Pyrus pyrifolia Nakai cv. Niitaka and Chuhwangbae). Total phenolic, flavonoid, and ascorbic acid contents in the peels were higher than those in the flesh. However, total tocopherol content between peels and flesh was not different. The peels exhibited higher free radical scavenging activities in the in vitro models of DPPH, ABTS + , nitrite radicals, and reducing capabilities than those of the flesh. Pear fruit extracts significantly prevented 3T3-L1 cells from undergoing H 2 O 2 -induced oxidation and the effect was higher by the peel extract than by the flesh extract. In addition, blood plasma of rats administered the peel extract showed higher antioxidative activity than that of rats administered the flesh extract. These results suggest that consumption of unpeeled Asian pear fruit may effectively increase antioxidant activity in the body.