Low Lysine Treatment Increases Adipogenic Potential of Bovine Intramuscular Preadipocytes
The molecular mechanism of adipocyte differentiation has been well documented. However, the effect of specific nutrients such as lysine on adipocyte differentiation is poorly understood especially in ruminant animals. Therefore, the aim of the present study was to elucidate the influence of lysine o...
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| Veröffentlicht in: | Animal bioscience 2009, 22(5), , pp.721-726 |
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| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
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| Online-Zugang: | Volltext |
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| Zusammenfassung: | The molecular mechanism of adipocyte differentiation has been well documented. However, the effect of specific nutrients such as lysine on adipocyte differentiation is poorly understood especially in ruminant animals. Therefore, the aim of the present study was to elucidate the influence of lysine on adipocyte differentiation and adipogenic genes in cultured bovine preadipocytes. The preadipocytes were treated with different concentrations of lysine (40, 160, 320 mg/L) or troglitazone (10 μM) for 2 days and then subsequently cultured in differentiation medium until day 6. Expression levels of C/EBPαwere significantly higher (p |
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| ISSN: | 2765-0189 2765-0235 |